Per- and polyfluoroalkyl substances (PFAS) are a group of man-made chemicals that have been in use since the 1940s, and are (or have been) found in many consumer products like cookware, food packaging, and stain repellents. PFAS manufacturing and processing facilities, airports, and military installations that use firefighting foams are some of the main sources of PFAS. PFAS may be released into the air, soil, and water, including sources of drinking water.

PFOA and PFOS are the most studied PFAS chemicals and have been voluntarily phased out by industry, though they are still persistent in the environment. There are many other PFAS, including GenX chemicals and PFBS in use throughout our economy.

GenX is a trade name for a technology that is used to make high performance fluoropolymers (e.g., some nonstick coatings) without the use of perfluorooctanoic acid (PFOA). HFPO dimer acid and its ammonium salt are the major chemicals associated with the GenX technology. GenX chemicals have been found in surface water, groundwater, finished drinking water, rainwater, and air emissions in some areas.

As part of EPA’s draft toxicity assessment, the agency has developed draft oral reference doses (RfDs) for GenX chemicals and PFBS. Learn more about EPA’s draft toxicity assessment on GenX. 

(Information from EPA Basic Information on PFAS webpage)